Phentermine vs other medicines

Phentermine Vs Other Medicines and Products for Obesity

, reviewed by
 – Updated May 8, 2023
, reviewed by
 – Updated May 8, 2023
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Phentermine is one of the world’s most popular and commonly used drugs for overweight or obesity. This status is due to its properties and undeniable benefits:

  1. Stable appetite suppression.
  2. 96% of people lose more than 5% of their weight after 3 months.
  3. 62% of people lose more than 10% of their weight after 3 months.
  4. The chances of losing 10% in 3 months are 13.3 times higher than those of people not using these diet pills.

These are the results of a study on the effectiveness of Phentermine published by the National Center for Biotechnology Information.

But how effective and helpful are other weight loss drugs? What are their advantages and disadvantages? Read on to find out.

Xenical vs Phentermine

Xenical, also known as Orlistat, belongs to a class of peripherally selective drugs. The TGA approved the drug in April 2000 for treating obesity in combination with a moderately low-calorie diet.

If we compare Xenical and Phentermine, the first drug has a number of benefits:

  • It works in the gastrointestinal tract.
  • It prevents the absorption of a third of dietary fats received with food.
  • It has a very low risk of cardiovascular side effects.
  • You can use it for a long time.

As for the effectiveness of this treatment, it is low enough. According to these data, weight loss is:

  • 6–10 kg for 12 months with Orlistat.
  • 6.4 kg for 3 months with Phentermine.

Lipozene vs Phentermine

It isn’t easy to compare Lipozene to prescription diet pills because Lipozene is a supplement. The TGA did not approve this supplement, and it is not an obesity treatment.

Although not clinically proven, there is evidence that Lipozene:

  • helps reduce weight;
  • absorbs water and expands 200 times in size;
  • does not cause side effects.

We found no reliable information about the average weight loss when taking Lipozene.

Phentermine vs Tenuate

Tenuate (the active ingredient Diethylpropion, also known as Amfepramone) is very similar to Phentermine. Both drugs:

  • stimulate the CNS;
  • suppress appetite;
  • are for short-term use.

According to a study, people who took Diethylpropion lost an average of 9.8% of their original body weight in 6 months.

It should be noted that the TGA did not approve Tenuate and other Diethylpropion-based drugs, and they are not available in Australia.

Phentermine vs Ephedra

They widely use Ephedra, including in folk medicine, as a remedy for peptic ulcer, rheumatism, malaria, stomach diseases, cardiovascular diseases, asthma, bronchitis, hay fever and obesity.

It is difficult to talk about the effectiveness of Ephedra in weight loss programs. According to Wikipedia, some studies demonstrate that Ephedra can cause short-term weight loss (0.9 kg more per month than placebo).

What vitamins should I take with Phentermine?

The weight loss process is not simple and sometimes fraught with many pitfalls. However, there are some vitamins, minerals, and trace elements you can take to keep your body functioning as effectively as possible while you are losing weight:

  • Zinc;
  • Selenium;
  • Chromium;
  • Iodine;
  • Magnesium;
  • Calcium;
  • Vitamin C;
  • Vitamin D;
  • B vitamins;
  • L-carnitine;
  • and others.

Supplements to take with Phentermine

According to the package leaflet posted by the TGA, before you start taking Phentermine, you must inform about all vitamins and supplements you are taking or intend to start taking. It is necessary to avoid drug interactions.

Supplements with lots of fiber, vitamins, or minerals can help break down stored body fat. Supplements that affect appetite, metabolism, or energy levels have great potential to interact with Phentermine.


The truth about Phentermine and other approved diet pills is that they do work, albeit with varying effectiveness. But you should be aware that you cannot lose weight without effort. It is impossible!

According to medical practice, weight loss medications increase the likelihood of clinically significant weight loss when you make appropriate lifestyle changes.

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