Phentermine and Prozac in combination

Phentermine and Prozac in Obesity Treatment

, reviewed by
 – Updated May 8, 2023
, reviewed by
 – Updated May 8, 2023
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Over the past few decades, obesity has become an issue in most developed countries and acquired the scale of a real epidemic. Being overweight is not only an aesthetic problem, but it also provokes the development of various pathological conditions. That is why experts from all over the world are searching for effective tools for weight loss. One of them is the combination of Phentermine and Prozac.

Phentermine is a potent drug approved for obesity treatment since 1959. It works on the central nervous system stimulating the release of serotonin and dopamine and also suppressing appetite. The medication can be taken under the supervision of a specialist following the recommended dosing. Usually, the drug is prescribed once a day, but in severe cases, when urgent weight loss is needed, it can be taken more often. However, the duration of therapy shouldn’t be long-term to avoid addiction and adverse reactions.

Prozac belongs to a class of antidepressants and can be indicated for bulimia nervosa and obsessive-compulsive disorder. It improves energy levels and mood and decreases fear, anxiety, and unwanted thoughts. A doctor prescribes the drug, and the effect of its use is noted within 2-4 weeks.

Possible Side Effects When Taking Phentermine and Prozac in Combination

A combination of these drugs for obesity treatment seems promising. Phentermine allows for reducing appetite, while Prozac makes up for the deficiency of substances responsible for good mood. As a result, a patient won’t experience psychological discomfort during the treatment. Moreover, it is known that obesity often develops against the background of depression, when food becomes the only joy in life.

Despite the safety of each drug separately, their combination raises concerns. Patients reported the following side effects:

  • Anxiety;
  • Nervousness;
  • Confused consciousness;
  • Hallucinations;
  • Jumps in blood pressure;
  • Tremor;
  • Constipation or diarrhea;
  • Blurred vision, etc.

In especially severe cases, a coma may develop. If you experience solid adverse reactions or an increase in their symptoms, you must report it to your doctor. Although many experts prescribe Prozac and Phentermine together for obesity treatment, there is no common opinion regarding this method among healthcare specialists: it is up to a particular doctor to decide.


Phentermine and Prozac belong to different classes of drugs, but they can be used together for obesity treatment. Moreover, they can intensify the effects of each other by increasing the manifestation of side effects up to confused consciousness and even coma. If a doctor has prescribed you a combination of these drugs, carefully monitor your health and report all negative symptoms to your physician.

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