Duromine vs. Phentermine

Last updated on May 8th, 2018

Comparing these two meds may seem an action that makes a little sense especially knowing that an active ingredient of the former is the latter. Still the medications differ, and that significant difference comes in a more prolonged effect and easier absorption that distinguish Duromine from Phentermine. So, let’s get further to the topic.

They are the same, though different


Amphetamine-like medication on the basis of which anti-obesity drugs are produced.


Popular brand name for Phentermine tablets and capsules.

Around 30 trade names of Phentermine have been sold worldwide during its more than 50 years of presence on the pharmaceutical market. Duromine is one of these.

Introduced onto the markets of Australia, New Zealand and South Africa in 1991, Duromine has become a major Phentermine-based weight loss medication recommended and prescribed during the next 24 years.

And it still is. Unlike many other Phentermine drugs withdrawn and phased out, Duromine remains number one anti-obesity medication within its major market area and not only. It is widely prescribed and recommended, preferred and chosen and the major reason for such popularity lies in the aforementioned prolonged effect and easier absorption Duromine is known for.

Phentermine was synthesized in the middle of the last century and was first approved for use in 1959 in the USA. Today Phentermine is available as:



Manufactured Drug Form Matters a Lot

The major differentiating factor that enables Duromine to bring greater efficacy than its basis, Phentermine, is its manufactured form.

Resin in pharma industry may seem not a big deal, but it is that timed-released agent owing to which Duromine is perfectly able to produce a remarkably lasting therapeutic effect without making a patient to significantly increase dosage.

Since Duromine is usually recommended in severe cases of obesity accompanied with comorbidities like hypertension, high cholesterol and diabetes, more lasting effect at fairly low dosing may matter a lot. In other words, Duromine slow-release resin is manufactured as it makes this medication a better alternative to not only Phentermine per se, but also to most other drugs containing this ingredient.

Concerns Expressed when Rating Duromine and Phentermine

Both Duromine and Phentermine are appetite suppressants. As such, they act similarly to Phentermine’s parent compound, amphetamine. They reduce perception of hunger by releasing four major chemicals responsible for satiation: noradrenaline, adrenaline, dopamine and serotonin.

Since such an effect may potentially cause adverse reactions, these drugs differ in concerns expressed by people who have ever taken either Duromine or Phentermine, or both.

According to the rating figures based on patients’ reviews and testimonials rather than clinical trials and information posted on the labels, Phentermine has a slightly lower level of concern.

This is probably due to the pharmacological features of Phentermine, such as:

  • rapid achievement of the maximum concentration in the blood;
  • a relatively shorter half-life;
  • rapid elimination from the body.

At the same time, both drugs are reported to be equally helpful. In regard to both points, it should be said that no review or vote can be taken as factual, as we cannot be sure that each and every patient has taken the prescribed med directly as indicated, properly combining it with diet and exercises.

Duromine or Phentermine: What Medication Can Be Just an Option?

Any medication of the two can be just an option. Everything will depend on that individual response your body can give to the therapy with either of the drugs. Likewise, other aspects, such as availability of generic versions and overall cost of each particular medication, will be decisive as well. Duromine is not a cheap drug. And since affordability of the treatment matters a lot now, such a factor, as it often happens, may become the primary one.