Duromine vs. Adipex

If you have been trying hard and put much effort to improve your weight, but everything was in vain and you did not receive a desirable effect, it is time to start medical treatment. The pharmaceutical researches and discoveries of the past few decades supplied people with multiple quality and effective drugs to treat obesity.

These are mainly Phentermine-containing drugs with their potent contribution to the work of the central nervous system. During further investigations, multiple Phentermine alternatives and derivatives have been created, with Adipex and Duromine being the most striking examples. Despite the fact that both medications contain Phentermine as an active ingredient, they have a range of differences.

Main differences between Duromine and Adipex

Hardly any patient who suffers from obesity is ready to waste time trying diverse medications and testing their effect on the body. Thus, it is inevitable to known various features of each medication and opt for the one suiting your needs and providing a desirable effect. Additionally, one should ensure a high safety level of the treatment course, based on health condition, related complications and other issues.

Thus, before taking either Duromine or Adipex, consult your healthcare provider; inform him/her about all the experienced health problems and medications you are taking to choose the safest variant. It will also help to prevent possible drug interactions and other dangerous reactions.

While Duromine and Adipex are the variants of the same med, they have multiple discrepancies. First of all, both medications are banned by some countries, for example, it is impossible to buy Duromine in the USA, while Adipex is not available in Australia.


Though, both drugs are accessible via online stores and can be delivered to any country. Another important difference between the two drugs is the function of the active component. Consequently, the effect produced by the drugs also varies.

Duromine contains Phentermine as a resin complex

It is available only as oral capsules containing 15 mg, 30 mg or 40 mg of the active ingredient.

Adipex contains Phentermine Hydrochloride

It is available as oral tablets and capsules containing only 37.5 mg of the active ingredient.

These two different chemical structures of Phentermine have different biopharmaceutical properties that have a great influence on:

  • rate of the active substance release;
  • duration of therapeutic action.

Phentermine release from Duromine capsules occurs gradually and evenly over a period of 24-25 hours* that helps:

  • maintain a stable level of the drug in the blood;

  • reduce the likelihood of side effects.

* Depending on the age and existing pathologies of the body.

As a result of slow release, the duration of the therapeutic effect is increased.

Release of active substance from Adipex pills occurs quickly. The maximum concentration of the drug in the blood is reached within 3-4 hours after its administration.

Adipex use provides:

  • rapid onset of anorexigenic effect;

  • powerful appetite suppression for 8 to 10 hours*.

* The duration of the therapeutic effect may differ depending on the body’s characteristics and the person’s age.

Drugs differ not only in pharmacokinetic parameters, but also in the dosing regimen:


  • One capsule / tablet 37.5 mg once daily, in the morning;
  • A half Adipex 37.5 tablet twice daily, 18.75 mg – in the morning and 18.75 mg – early in the afternoon.


  • A 15 mg, 30 mg or 40 mg capsule once daily.
  • A 15mg capsule twice daily (in the morning and in the afternoon).

While Adipex is most commonly prescribed to patients with severe obesity cases and accompanying health issues, such as heart problems, high cholesterol level, diabetes of any type, high blood pressure, etc., Duromine is frequently prescribed for both seriously obese and pre-obese patients.

Considering the price difference of Duromine and Adipex, it is necessary to note that the cost of the meds depends mainly on the country. However, you always have an opportunity to order both drugs online at rather moderate and reasonable prices.

What is common between Duromine and Adipex?

The most important peculiarity of these two drugs is the category they belong to – effective weight loss medications. Besides, despite minor differences in the form of an active component, Adipex and Duromine produce a drastic and powerful effect, contributing to the work of the central nervous system.

Besides, both medicines are only a part of the full weight loss treatment, as they should be combined with regular physical exercises and constant low-calorie diet.

Moreover, Duromine, as well as Adipex share the same administration recommendations and restrictions. The drugs should be taken one hour before breakfast or two hours after it. It is not allowed to take:

  • Adipex if you are younger than 16 years old.
  • Duromine if you are younger than 12 years old.

Follow your doctor’s recommendations to avoid treatment misuse or overuse with all the potential side effects that may appear as the result.