Victoza Vs Ozempic. Effective for diabetes type 2

Victoza Vs Ozempic: What Medicine is More Effective for Type 2 Diabetes?

By 
, reviewed by
 – Updated January 12, 2023
By 
, reviewed by
Linley-Boulden
 – Updated January 12, 2023
Table of Contents
Table of Contents

Victoza and Ozempic are GLP-1 agonists used for two main purposes:

  • Lower blood sugar levels for people with type 2 diabetes;
  • Lower the risk of some cardiovascular problems for adults with type 2 diabetes.

TGA and FDA approved both drugs for these purposes. Both drugs have the same manufacturer — Novo Nordisk.
Consider the similarities and differences between these two drugs:

VictozaOzempic
Active ingredientLiraglutideSemaglutide
Other brandsSaxendaRybelsus, Wegovy
Dosage formSubcutaneous injections, pre-filled injection pens
Drug classIncretin mimetics
Generic availabilityNo
Administration frequencyOnce a dayOnce a week
Half-life period13 hours168 hours
Dosage
  • Starting dose: 0.6 mg.
  • Standard dose: 1.2 mg.
  • Maximum dose: 1.8 mg once a day.
  • Starting dose: 0.25 mg.
  • Standard dose: 0.5 mg.
  • Maximum dose: 1 mg once a week.
Treatment durationNot exactly established
Intended forAdults and children of 10 years and olderAdults over 18 years old
Use with caution for people with the following diseases
  • Pancreatitis;
  • Family and/or personal history of thyroid cancer;
  • Depression;
  • Kidney dysfunction;
  • Cardiovascular diseases
  • Suicidal behaviour and thoughts;
  • Family and/or personal history of thyroid cancer;
  • Hypoglycemia;
  • Pancreatitis;
  • Retinopathy
Complex treatmentTo enhance the effect, they combine them with diet and exercise
Type 1 diabetes treatmentNo
Most frequent common side effectsProblems with the gastrointestinal tract:

  • Nausea;
  • Vomiting;
  • Diarrhea or constipation
Specific side effects
  • Headache;
  • Cold;
  • Backache
  • Stomach ache
Use during pregnancyNot recommended
Compatibility with alcoholIt is recommended to exclude alcohol for the entire period of treatment

What medicine is more effective?

According to a study published in 2019, Ozempic was more effective than Victoza in reducing HbA1C and weight. However, participants in this meta-analysis who took Ozempic experienced more stomach-related side effects than people who took Victoza.
However, only a doctor who can take into account the entire history and characteristics of your body can prescribe the most suitable medicine for you.

Conclusion

The action of Victoza and Ozempic is similar in many aspects.

They differ by:

  • Active ingredient;
  • Age of people for whom the use is approved;
  • Frequency of use;
  • Dosage;
  • Some side effects.

In a comparative analysis, Ozempic showed higher effectiveness. However, the number and frequency of side effects were also higher.

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