Comparing weight loss medications is not easy, especially if you are not a healthcare professional. We’ve decided to take a shot and present the information clearly. Comparison is based on the latest data from reliable sources.
Let’s start with the most prominent difference.
Of course, we are talking about the lost kilos. This marker shows the effectiveness of a drug.
Manufacturers of these injections inform that if a person’s weight is 95 kg, they may lose:
- 17.3 kg on Semaglutide (after 68 weeks) – (details of the clinical program).
- 4.6 kg on Trulicity (after 52 weeks) – (details of the clinical program).
It must be mentioned that the trials lasted for different periods of time, and the drugs weren’t compared with one another. Nevertheless, it is evident that Semaglutide is almost three times more effective than Trulicity.
Now, let’s discuss other differences.
| Trulicity | Semaglutide | |
| Indications | Type 2 diabetes | Obesity, overweight, type 2 diabetes |
| The time when the highest dosage may be used | 3 months | 4 months |
| Half-life | Approximately 113 hours | Approximately 170 hours |
| A similarity to human GLP-1 | 90% | 94% |
| Can be left out of the fridge | Up to 14 days | Up to 42 days |
| Entered the pharmaceutical market | In 2014 | In 2021 |
Is Semaglutide the Same as Trulicity?
No, it is not true.
These are different medications, but they have much in common:
- Act as a satiety enhancer.
- Help to decrease the level of waist circumference and fat in the body.
- The liquid solution is delivered in a medical device (pen-injector).
- The dosing regimen is 1 dose per 7 days.
- The treatment starts with the lowest dose, which will be gradually increased.
- The drug is injected under the skin of your stomach, thighs, or upper arm.
- Comparable adverse effects profile.
- Classified among GLP-1 RA group of drugs.
These are the key similarities of the drugs.
Semaglutide vs Trulicity: Conclusions
We consider that this comparison may be helpful to our readers and people who fight obesity. Now, you are aware of the differences and similarities of these drugs.
Can we state that Semaglutide is better than Trulicity for anyone under any circumstances? Of course, no. People are different, and they may have different reactions to a drug.
However, there are clinical trial results that can’t be ignored. Conclusions on the efficacy of obesity treatment should and must be made based on the trials.
