Phentermine and Ritalin taken together

Phentermine Vs Ritalin: Similarities and Differences

, reviewed by
 – Updated May 8, 2023
, reviewed by
 – Updated May 8, 2023
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Many use well-known and proven products such as Phentermine for an effective weight loss remedy. But other drugs can help in weight loss. Let’s compare Phentermine vs Ritalin and find out what their differences are.

Both drugs are CNS stimulants. They directly affect the nervous system leading to increased metabolism and suppression of appetite. The exact mechanism of action causes similar side effects, such as:

  • Irritability;
  • Insomnia;
  • Dry mouth;
  • Increased heart rate;
  • Increased blood pressure, etc.

The drugs also have significant differences:

Active ingredientPhenyl tertiary butylamineMethylphenidate
Principle of actionIt increases the level of serotonin and norepinephrine, speeds up the metabolism and reduces hungerIt improves attention concentration and makes it possible to control behavior and hunger
UseTo treat obesityTo reduce appetite while reducing calorie intake
Treatment durationShort-termShort-term

The main difference between the drugs is that originally Phentermine was for fighting obesity and Ritalin was for treating behavioral disorders such as ADHD. Its effect in treating obesity is due to the ability to control appetite. Given the differences in the action, the weight can also return after stopping Ritalin and returning to the previous calorie intake.

Phentermine and Ritalin taken together is a dangerous combination

Although both drugs affect the CNS and have similar effects, they have different chemical compositions, and Phentermine and Ritalin taken together are dangerous. Simultaneously using these drugs can cause serious side effects, including cramps.

According to a study involving 87 people, while taking Phentermine and Ritalin, the subjects observed the following disorders:

  • 59 people had sleep-wake cycle disorders;
  • 47 people reported the loss of muscle tone while conscious;
  • 6 people developed multiple sclerosis;
  • 5 people complained of pain.

So, the combination of Phentermine and Ritalin is undesirable and should be under the control of a doctor. It doesn’t enhance the effect of the use of drugs and doesn’t contribute to rapid weight loss. It is wiser to choose one of them and focus on lifestyle changes. Review your diet and add exercise, as the results will be temporary without them. Weight loss takes effort: there is no magic pill that works for you.


You can use Phentermine and Ritalin to lose weight in a short time. The drugs have a similar effect, but you shouldn’t take them together. In some cases, this combination can lead to serious consequences. To increase the effectiveness of treatment while taking the drugs, you should add physical activity and change your diet.

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