wegovy and trulicity

How Does Wegovy Work: Difference Between Wegovy and Other Drugs

, reviewed by
 – Updated April 19, 2023
, reviewed by
 – Updated April 19, 2023
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Today, millions of people are facing obesity and overweight problems. Common recommendations, which are reduced to changing a diet and putting more physical activity into your daily schedule, don’t give the desired effect. It is especially challenging for people with a lot of excess weight. A new medication Wegovy has become their salvation. However, there are other drugs that promote weight loss. Let’s compare them to Wegovy and find out how they differ.

Wegovy vs Trulicity for weight loss: what medication is safer?

Wegovy has become a revolutionary weight loss drug developed to fight obesity. At the same time, many people believe that there are alternative drugs that are no less effective. For example, some patients consider Wegovy and Trulicity analogues. Both drugs are given by injection and help lose weight, but it doesn’t mean that Trulicity can be used only for weight loss.

The fact is that the difference between Wegovy and Trulicity is huge. It refers to the drugs’ indications: Trulicity is used to treat type 2 diabetes, particularly to control blood sugar and reduce cardiovascular risk in people with diabetes. Weight loss is a consequence of treatment, not its purpose.

Is Wegovy and Trulicity the same: the ingredients of the drugs

Is Trulicity the same as Wegovy if you look at the composition of the drugs? No, it is not. The latter’s active ingredient is Semaglutide, while Trulicity contains dulaglutide as an active ingredient.

The difference in the active ingredient causes differences in the drug’s indications. Thus, only Wegovy was approved by the TGA for obesity treatment. Trulicity can be used exclusively by people diagnosed with type 2 diabetes with high blood sugar levels. Although the active substances of both medications are classified as GLP-1 receptor agonists, they have different dosing and are intended for other purposes.

Wegovy vs Metformin: what’s the difference?

Metformin can help you lose weight. However, can we compare Wegovy and Metformin? This drug is indicated to help lower blood sugar in patients with type 2 diabetes. That is why the TGA didn’t approve it for obesity treatment. But by taking this medication, you can lose weight because you feel less hungry when the blood sugar level comes down. However, this mechanism has not been extensively studied, and weight loss, in this case, is more likely a side effect.

Can you take Wegovy and Metformin together, and why?

These medications differ in the method of taking them. The first is administered by injection, and the second is taken orally. Besides, the drugs have different active ingredients. Currently, no interactions were found between them, so these medications can be used together. However, you should consult your doctor to avoid possible adverse reactions and estimate the usefulness of such therapy.

Wegovy and Adderall: comparison of the drugs

You may come across Adderall among various medications when it comes to weight loss. What kind of drug is it, and can it be compared with Wegovy? The answer is no.

Adderall is usually prescribed to treat ADHD and narcolepsy. One of its side effects is loss of appetite. That is why people who take Adderall can lose weight, but it is a side effect compared to a drug indicated for obesity treatment.

Can you take Wegovy and Adderall together or not?

These medications belong to different classes of drugs and are supposed to solve other problems, so you may combine them if needed. You should inform your doctor about the medicines you take so that they can consider the safety of co-administration. If you experience any adverse reactions or any deterioration in health, consult a medical specialist.

Wegovy vs Victoza: what is the difference?

Victoza is another medicine to treat patients with type 2 diabetes. It is used for glycemic control and the prevention of cardiovascular disease in people with diabetes. Liraglutide is the active ingredient of Victoza. The medication is a pre-filled injectable pen administered subcutaneously.

Is Wegovy the same as Victoza or not?

Liraglutide is the GLP-1 receptor agonist as well as semaglutide, the active ingredient of Wegovy. However, the amount of the active substance in Victoza is intended for decreasing blood sugar. In contrast, the active ingredient in the weight loss drug is used to suppress appetite and manage weight.

Even though you can lose weight with both medications, using Victoza in patients who don’t have diabetes leads to a high risk of side effects. If you want to get rid of extra kilos, choose the drugs indicated for this.

Imcivree vs Wegovy: the main difference

Imcivree is indicated for obesity treatment and control over hunger, but it is prescribed only to those who have genetic mutations, including:

  • Bardet-Biedl syndrome;
  • mutation in the POMC gene;
  • leptin receptor deficiency.

A doctor can prescribe the drug for such obese patients from age 6. Genetic testing to detect pathology is carried out before the prescription.

Liraglutide vs Wegovy: what to choose for weight loss

Liraglutide is used in the therapy of type 2 diabetes to control blood glucose levels and prevent complications of the cardiovascular system. It is an injectable medication to help people with diabetes lose weight. It isn’t suitable for other obese patients who want to get rid of extra weight. Wegovy is indicated exclusively to treat obesity and its related complications.

Differences between Wegovy vs Сontrave

Contrave is used to combat overweight and obesity. It contains naltrexone (addiction-reducing) and bupropion (antidepressant). The medication decreases the sensation of hunger and helps reduce the amount of food by influencing brain parts involved in controlling appetite and food cravings. Contrave is taken orally for a long time. Its mechanism of action is different from Wegovy, which mimics a human’s satiety hormone.

Wegovy and Topamax in obesity treatment

Тopamax is prescribed to people who suffer from epilepsy and migraines. It is classified as an anticonvulsant drug. During treatment, you may lose weight due to a decreased appetite provoked by the medication. Some animal studies have shown its ability to increase metabolic rate. But Тopamax is not approved for obesity treatment. If Wegovy has a recommended dosing and treatment plan for weight loss, Тopamax doesn’t have this data.

Difference between Wegovy vs Qsymia

Qsymia is also indicated to fight against overweight and obesity. It is taken orally daily, unlike Wegovy, which is injected once a week. Qsymia is a combination of phentermine and topiramate, while the active ingredient of a weight loss drug is semaglutide. They have different mechanisms of action, but both lead to appetite reduction and weight loss.


Wegovy is a GLP-1 agonist used exclusively to combat overweight and obesity. It has a specific treatment plan and the necessary dosage. Even though there are a number of other medications that can promote weight loss, it is unsafe to use them for this purpose because they are indicated for different conditions and diseases. Using them for other purposes, you can experience harmful side effects. If your main goal is getting rid of extra kilos, you should choose drugs that are developed explicitly for this.

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