semaglutide how work

How Does Semaglutide Work? All the Particularities and Subtleties of the Drug’s Effect on the Body

, reviewed by
 – Updated May 15, 2023
, reviewed by
 – Updated May 15, 2023
Table of Contents
Table of Contents

How does Semaglutide work? How does it facilitate weight loss? If you are wondering, you should read and understand its intended use. Semaglutide was approved by the TGA (Therapeutic Goods Administration) after many studies related to its effects on type 2 diabetes mellitus.

The results showed that the drug contributed to significant weight loss. Therefore, it was also approved as an anti-obesity medication for people with a BMI (body mass index) above 30 per cent.

Semaglutide belongs to incretin mimetics, i.e., it stimulates your body to produce the right amount of insulin. In addition, it increases energy and reduces appetite.

GLP-1 mimicking distinguishes the drug from other anti-obesity medications produced by the body after eating. The small intestine produces this hormone naturally, however, with a very short-term effect. Semaglutide mimics the synthetic production of GLP-1, resulting in earlier and longer satiety.

This effect reduces the number of calories consumed, increases energy, and stimulates weight loss.

How long does Semaglutide take to work for weight loss?

How long does Semaglutide take to work for weight loss? A 56-week formal study of the drug helped determine it. During the entire experiment, the participants lost an average of about 5% of their weight. While the patients injected for 68 weeks lost 14.9% of extra pounds.

The effect is perceptible in the early stages when the drug dose increases to the maximum. During this period, you can lose up to 30 pounds. Based on the available data, you can lose about 15% of excess fat within six months from the start of the drug if you do not suffer from any severe concomitant diseases and observe a healthy diet with a minimum of physical activity.

How long does a Semaglutide pen last? Peculiarities of the pen and instructions for use

How long does a Semaglutide pen last? First, you need to read the instructions. The above is also essential before the first injection. Semaglutide differs from other injections because you must inject it once a week. Its full dose is 1.0 mg per week. However, it would help if you reached it gradually according to your doctor’s prescription.

Each pen contains four injections, enough for a month of use and is already configured for a specific dosage. Therefore, there is no need to adjust the dose yourself.

The kit includes four needles, from which you need to remove the paper tongue and then insert it into a plastic cap. Turn it clockwise to secure the needle. Then fill the pen with the available solution.

Check the dial: if it indicates zero, the drug is secured and ready for use. Turn it by one and inject. Wait until the mark on the dial reaches zero again, count to ten and slowly pull out the needle. After that, close the handle with the cap, pull them out and dispose of them properly.

Remember that every time before using your pen, you must use a new needle!


The effect of Semaglutide is a few-week delayed. However, use the drug for six months to achieve the best results in weight loss. A lot depends on your initial weight and lifestyle. Follow a diet and exercise to achieve the best effect in the shortest possible time.

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