Duromine with Antidepressants

Last updated on May 23rd, 2018

Can Duromine be used with antidepressants? – This topical question is asked by many people treating obesity. This is because obesity is often accompanied with depression. It happens that:

  • depression causes uncontrolled hunger that leads to increase in body weight;
  • weight problems lead to depression and to even greater weight gain.

Never use Duromine with antidepressants without first consulting your doctor. Duromine and depression treatment drugs have similar mechanism of action, but they have different effects.

Duromine affects the brain parts responsible for appetite control and energy balance in the body.

Affecting the brain, Duromine suppresses appetite and may cause such side effects as nervousness and depression.

Antidepressants affect activity of neuroreceptors responsible for the person’s mood and mental health.

Affecting the functions of the central nervous system, antidepressants reduce depression symptoms and may lead to weight loss.

Duromine is contraindicated in patients with depression. Antidepressants in turn are contraindicated in patients who take Duromine, amphetamine-like psychostimulant.

If obese patient cures depression, he can be prescribed with Duromine only after he will stop taking antidepressants. Herewith, Phentermine-containing drugs can be prescribed only to those patients who have no significant symptoms of anxiety and depression.

In some cases, Duromine should not be used even after depression treatment. For example, obese patients with depression, who took drugs of the group of monoamine oxidase inhibitors (MAOIs), can begin taking Duromine no earlier than 2 weeks after discontinuation of their use.

A list of MAOIs includes several oral and injectable drugs, including:

  • Tranylcypromine (Parnate);

  • Selegiline (Eldepryl);

  • Moclobemide (Manerix);

  • Phenelzine (Nardil);

  • Isocarboxazid (Marplan).

Men and women, who have taken tricyclic antidepressants or serotonin reuptake inhibitors (SSRIs) to treat depression, should use Duromine with caution.

These antidepressants can interact with Duromine or any other appetite suppressants.

The patient should inform the doctor if he is taking any of these antidepressants, including:

  • Doxepin
  • Imipramine
  • Protriptyline
  • Paroxetine
  • Sertraline
  • Fluoxetine

As a result of Duromine interaction with such drugs, the following serotonergic side effects may develop:

  • Confusion
  • Agitation
  • Headache
  • Perspiring heavily
  • Loss of muscle coordination

If the patient used Duromine with antidepressants and side effects mentioned above appeared, he must seek medical assistance as soon as possible.

If depression and anxiety symptoms appear during or after the discontinuation of Duromine use, such symptoms may indicate that the dose of these diet pills has not been matched correctly.

To minimize the risk of developing depression and avoid the need for using antidepressants, follow the recommendations for Duromine use.

15 mg, 30 mg or 40 mg capsules are used once daily

The maximum daily dose should not exceed 40 mg

If you experience depression or other side effects, Duromine dose can be reduced. To avoid depression development at the end of the treatment, it is better to gradually reduce the daily dose.