Coffee and Phentermine

Caffeine and Phentermine: What Are the Risks of Taking Them Together?

, reviewed by
 – Updated May 8, 2023
, reviewed by
 – Updated May 8, 2023
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Table of Contents

Phentermine belongs to the category of psychostimulants and is indicated for obesity treatment. It should be carefully combined with other medications because they may intensify each other and cause severe side effects. How do caffeine and Phentermine interact? What should you know about taking them together?

Phentermine stimulates the central nervous system, reducing appetite and improving metabolism. Usually, it is prescribed for 3-6 weeks. Caffeine also has a mild stimulating effect on the CNS, but it is less pronounced compared with Phentermine. Besides, due to the similar mechanism of action combination of Phentermine and caffeine may increase the following side effects:

  • Insomnia;
  • Rise in blood pressure;
  • Anxiety;
  • Rapid heartbeat, etc.

Thus, specialists recommend avoiding drinking caffeine if you use Phentermine. Considering the fact that caffeine is found in other drugs and food products, you should carefully study its composition.

Each patient may have different adverse reactions: some people don’t experience any discomfort when taking caffeine and Phentermine, while others may have severe side effects. People with cardiovascular disease are at special risk.

Coffee and Phentermine: drink or not to drink?

Many people can’t imagine starting a day without a cup of aromatic coffee. This drink helps them to wake up and feel vigorous and active. Such an effect is associated with caffeine contained in coffee. Can coffee and Phentermine be combined? Do you have to give up on your favorite drink if you take a weight loss drug?

As mentioned above, caffeine acts as a CNS mild stimulant, and it can increase adverse reactions from Phentermine in large quantities. If you are a coffee lover, you will have to quit drinking 6 cups of coffee a day to avoid problems with your health. However, one cup of coffee daily won’t harm you.

If you can’t limit yourself to one cup, you may try decaffeinated coffee. This drink will be safer while taking Phentermine. The fundamental rule: keep balance and be careful with coffee not to provoke jumps in blood pressure and increased heart rate.

The best solution is to avoid coffee for some time. Considering that the Phentermine treatment course is usually short, you will be able to survive without coffee. Otherwise, discuss the possibility of drinking coffee while taking the drug with your doctor.


Caffeine and coffee help us to be active and improve our mood; that is why we can’t do without them so often. However, you’d better avoid them while taking Phentermine so as not to have unpleasant side effects. For those who can’t live without coffee, decaffeinated coffee may become a lifesaver. If you can’t give up drinking coffee, discuss the possibility of taking it during the treatment course with your doctor.

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