What Does Duromine Contain? The Ingredient That Matters

Last updated on May 28th, 2018

What does Duromine contain? It is one of the most frequent questions asked whenever treatment with this medication is recommended.

Patients, who have already received a prescription for Duromine, know that this drug is included in the group of controlled substances (Schedule 4 in Australia), but do not know for sure what that actually means.

In order to avoid any misconception expressed in relation to the medication, we are going to give an answer to this question in detail.

Duromine: About the Major Ingredient

An active ingredient of Duromine is Phentermine. Phentermine is a compound pharmacologically similar to Amphetamine. This is the peculiarity that usually raises all those questions most patients have when receiving treatment with any Phentermine-based drug, Duromine including.

phentermine formula

Indeed, Amphetamine and Phentermine are usually mentioned as structurally/chemically/pharmacologically similar compounds, but in reality these are different medications with different tasks.

Phentermine is approved only for treatment of overweight and obesity in patients with a BMI of 27 and above.

Amphetamine is used to treat Attention Deficit Hyperactivity Disorder (ADHD).

Phentermine (Duromine) is an appetite suppressant and belongs to the class of drugs called sympathomimetic amines.

This drug exerts its anorexic effect via reuptake inhibition by a particular group of neurotransmitters, which may induce satiety. This group includes the following neurotransmitters:





A high level of these neurotransmitters helps suppress hunger signals in the brain and helps the obese patient to control appetite throughout the day.

It is believed that Phentermine can suppress activity of monoamine oxidase enzyme that leads to an increase in the level of the above-listed neurotransmitters in the synapse.

Due to its properties, Phentermine can also indirectly affect the leptin level in the brain. Leptin is a satiety hormone that regulates energy metabolism and transmits a signal to the hypothalamus that the body has already received the required amount of nutrients. In response to the hormone action, the brain gives the command to reduce the appetite and the person ceases to feel hungry.

That’s what Phentermine (Duromine) does – increases the levels of the chemicals in the brain reducing the perception of hunger.

In other words, the major ingredient of Duromine, Phentermine, controls your appetite making you less hungry.

This effect, when combined with a healthy diet and regular training, helps you lose weight easily and steadily. Duromine is absorbed in the stomach during the whole day bringing a greater effect than any drug belonging to the group of Phentermine-based medications.